A Clinical Study of the Effect of Nishalauha choorna in the Management of Hepatitis (Kamala)

Jayawardhana N.D.N, Tiwari S.K.

Abstract

A Clinical Study of the Effect of Nishalauha choorna in the Management of Hepatitis (Kamala)
Jayawardhana N.D.N¹*, Tiwari S.K.²

Abstract
Hepatitis is an inflammatory condition of the liver which correlated with the Kamala in Ayurveda. Kamala is a Rasa and Rakta dhatugata, Pittaja nanatmaja and Raktavaha srotodushtijanya vyadhi. Although, there is a high prevalence of Kamala, minimum number of sufficient clinical studies constructed to find the effectiveness of the formulae on Kamala. Therefore, this clinical study was conducted to evaluate the therapeutic efficacy of Nishalauha choorna on Kamala patients. Randomly selected twenty-two patients who were attended to the Sir Sunderlal Hospital, India and suggestive of Kamala/Hepatitis in history, clinical signs and symptoms and laboratory investigations especially by doing hepatitis profile were included in this study. The prepared Nishalauha choorna 5gm given to those patients orally twice a day after meals with 5 ml bee honey and 2.5 ml Ghee for a period of three months and signs and symptoms and laboratory investigations were determined before and after the treatments. The efficacy of the Nishalauha choorna was evaluated by the improvement of signs and symptoms along with the laboratory findings. Statistical analysis was calculated by using mean and standard deviation, Kruskal Wallis H test, Friedman and Chi square test. The results showed markedly significant improvement of the symptoms such as status of Agni and Ama (P<0.01), abdominal pain, abdominal tenderness, burning sensation, easy fatigability, anorexia, clay colour stools, nausea, vomiting, fever and pruritus (P<0.001). And also, there was a significant influence (p<0.001) on SGOT, direct bilirubine, indirect bilirubine and serum alkaline phosphatase at the end of the three months of treatment period. Hence, it can be concluded that the Nishalauha choorna is effective in the treatment of Hepatitis/ Kamala.

Keywords: Hepatitis, Kamala, Nishalauha choorna

¹Department of Ayurveda, Institute of Indigenous Medicine, University of Colombo, Sri Lanka.
²Banaras Hindu University, [BHU], Varanasi-221005, U.P., India.

Correspondence: Dr. N.D.N. Jayawardhana, Unit of study in Kayachikithsa, Department of Ayurveda, Institute of Indigenous Medicine, University of Colombo, Sri Lanka. Email: namalayur@iim.cmb.ac.lk